Dr. Noor Mohammad
Lecturer
Contact
Email: noor@che.buet.ac.bd
Office: Ground floor, DChE, Old Academic Building, BUET, Dhaka-1000.
Education
Ph.D. in Chemical Engineering
North Carolina State University, USA (2024)
M.Sc. in Chemical Engineering
Bangladesh University of Engineering & Technology (BUET), Dhaka (2018)
B.Sc. in Chemical Engineering
Bangladesh University of Engineering & Technology (BUET), Dhaka (2016)
Research Interest
Biotechnology, CRISPR-DX and biosensing, POCT, Microfluidics, Infectious disease and global health, Environmental pollution
Publications
Journal Articles (Peer Reviewed)
- N. Mohammad, L. Talton L, S. Dalgan, Q. Wei*. A Ratiometric Nonfluorescent CRISPR Assay Utilizing Cas12a-Induced Plasmid Supercoil Relaxation. Commun. Chem. 2024, 7, 130.
- Z. Hetzler, S. Marinakos, N. Lott, N. Mohammad, A. Lass-Napiorkowska, J. Kolbe, L. Turrentine, D. Fields, L. Overton, H. Marie, A. Hucknall, O. Rammo, H. George, and Q. Wei*. Rapid Adeno-Associated Virus Genome Quantification with Amplification-Free CRISPR-Cas12a. Gene Ther. 2024, 31, 304.
- S. Jamalzadegan, S. Kim, N. Mohammad, H. Koduri, Z. Hetzler, G. Lee, M. D. Dickey*, Q. Wei*. Liquid Metal-Based Biosensors: Fundamentals and Applications. Adv. Funct. Mater. 2024, 2308173.
- T. Shymanovich, A. Saville, N. Mohammad, Q. Wei, D. Rasmussen, K. Lahre, D. Rotenberg, A. Whitfield, and J. Ristaino*. Disease progress and detection of a California resistance breaking (RB) strain of tomato spotted wilt virus (TSWV) in tomato with LAMP and CRISPR-Cas12a assays. PhytoFront. 2024, PHYTOFR05-23-0058-FI.
- N. Mohammad, L. Talton, Z. Hetzler, M. Gongireddy, Q. Wei*. Unidirectional Trans-Cleaving Behavior of CRISPR-Cas12a Unlocks for an Ultrasensitive Assay Using Hybrid DNA Reporters Containing a 3′ Toehold. Nucleic Acids Res. 2023, gkad715.
- Z. Weng†, Z. You†, J. Yang, N. Mohammad, M. Lin, Q. Wei, X. Gao*, Y. Zhang*. CRISPR-Cas Biochemistry and CRISPR-Based Molecular Diagnostics. Angew. Chem. Int. Ed. 2023, 62, e202214987.
- N. Mohammad, S. S. Katkam, and Q. Wei*. A Sensitive and Nonoptical CRISPR Detection Mechanism by Sizing Double-Stranded λ DNA Reporter. Angew. Chem. Int. Ed. 2022, e202213920.
- N. Mohammad, S. S. Katkam, and Q. Wei*. Recent Advances in Clustered Regularly Interspaced Short Palindromic Repeats-Based Biosensors for Point-of-Care Pathogen Detection. CRISPR J. 2022, 5, 500-516
- L. A. Stanciu*, Q. Wei, A. K. Barui, and N. Mohammad. Recent Advances in Aptamer-Based Biosensors for Global Health Applications. Annu. Rev. Biomed. Eng. 2021, 23, 433-459.
- N. Mohammad, S. Sikder, M. S. I. Bhuiyan, S. Ahmed*. Comparative Assessment of Growth and Morphological Responses Reveals Resilience of HeLa cells over Vero Cells on Exposure to Arsenic (III). Asian J. Pharm. Hea. Sci. 2020, 10(2), 2291-2302.
Conference Presentations:
- N. Mohammad, A. Velayati, Y. Tang, A. Steksova, L. Huang, S. Zhang, A. Poonam, S. Jamalzadegan, M. Breen, G. Jiang, and Q, Wei, ” Label-free ratiometric CRISPR assay for low-cost detection of HIV”, Rising Stars in Analytical Chemistry, ACS Fall 2024 National Meeting. Denver, CO, Aug 19, 2024.
- Z. Hetzler, S. Marinakos, N. Mohammad, A. Lass-Napiorkowska, J. Kolbe, L. Overton, H. Marie, A. Hucknall, O. Rammo, H. George, and Q. Wei, ” Adeno-associated virus empty-to-full capsid quantification with CRISPR-Cas12a and washing-free immunosandwich assay”, Rising Stars in Analytical Chemistry, ACS Fall 2024 National Meeting. Denver, CO, Aug 18, 2024.
- N. Mohammad, L. Talton, Z. Hetzler, M. Gongireddy, Q. Wei, “Preferential Trans-Cleaving Behavior of CRISPR-Cas12a Towards 3′-Overhang dsDNA Unlocks to Develop Ultrasensitive Hybrid DNA Reporter”, Student Competition in Sensors (Sponsored) 2023 AIChE Annual Meeting, Orlando, FL, Nov 6, 2023. (Secured the first place in this oral session competition)
- Z. Hetzler, S. Marinakos, N. Lott, N. Mohammad, A. Lass-Napiorkowska, L. Turrentine, D. Fields, L. Overton, O. Rammo, H. George, and Q. Wei, “A Platform CRISPR-Cas12a Assay for Rapid Quantification of AdenoAssociated Virus Vector Genome Titers”, Biosensors for Nucleic Acids, 2023 AIChE Annual Meeting.
Orlando, FL, Nov 6, 2023. - O. Hossain, Y. Wang, M. Li, S. Jamalzadegan, N. Mohammad, A.D. Poonam, and Q. Wei, “Development of a Dual-Functional Microneedle-based Colorimetric VOC Sensing Technology for Onion Variety Differentiation”, 2023 AIChE Annual Meeting, Orlando, FL, Nov 7, 2023.
- N. Mohammad, “CRISPR-Cas12a-based Point-of-Care Detection Using dsDNA as Inexpensive and Nonfluorescent Reporter Molecule”, 2023 Schoenborn Graduate Research Symposium, Raleigh, NC, Oct 3, 2023.
- N. Mohammad, L. Talton, S. Dalgan, Q. Wei, “CRISPR-Cas12a-Induced DNA Supercoil Relaxation for Nonfluorescent Ratiometric DNA Detection”, 2023 BMES Annual Meeting, Seattle, WA, Oct 13, 2023.
- Z. Hetzler, S. Marinakos, N. Lott, N. Mohammad, A. Lass-Napiorkowska, L. Turrentine, D. Fields, L. Overton, O. Rammo, H. George, and Q. Wei, “Rapid Adeno-Associated Virus Vector Genome Quantification with Amplification-Free CRISPR-Cas12a Diagnostics”, Cell and Gene Therapies, ACS Fall 2023 National Meeting, San Francisco CA, Aug 13, 2023.
- N. Mohammad, S. Katkam, and Q. Wei, “Nonfluorescent CRISPR-Cas12a Biosensor By Sizing λ DNA”, Student Competition in Sensors (Sponsored), 2022 AIChE Annual Meeting, Phoenix, AZ, Nov 14, 2022.
- N. Mohammad, S. Katkam, and Q. Wei, “Ultrasensitive CRISPR-Cas12a Assay Using λ DNA as Reporter Molecules”, Microfluidics/Paper-Based Diagnostics, ACS Fall 2022 National Meeting, Chicago, IL, Aug 21, 2022.
- N. Mohammad, S. Sikder, M. S. I. Bhuiyan, S. Ahmed. “Cytotoxic Effect of Arsenic on the Growth and Morphological Responses of Mammalian Cells,” Asian Federation of Biotechnology Regional Symposium, Dhaka, 2018.
- N. Mohammad, S. Sikder, M. S. I. Bhuiyan, S. Ahmed. “Cellular Responses to Arsenic Exposure Leading to Different Carcinoma.” ICCHE, Dhaka, 2017.